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JBADGroup
Posted: Wed Jul 16, 2008 7:22 am    Post subject: Fascinating new study on Aging and Alzheimer's Reply with quote

Forum Freshman
Forum Freshman

Joined: 16 Jul 2008
Posts: 1

Hi all,
I would like to take the chance to give a link to a new and exciting study on so called Epigenetic effects in Alzheimer’s disease. It was published today at the PLoS ONE Journal website (http://www.plosone.org/home.action ; free access ).
It is a study on the effects of epigenetic (cellular information that is not stored in the DNA code) modifications in Alzheimer’s disease. The implications from this study are highly intriguing. The article is entitled “Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease” and can be accessed online at http://www.plosone.org/doi/pone.0002698 .

basically, it could be shown that Alzheimer patients differ from 'normal' persons by special chemical modifications which are attached to their DNA. These modifications (for example, DNA methylation groups) change with age and may be affected by environmental influences, e.g. diet or toxins.

We believe that this excellent and timely study will change the view on Alzheimer’s disease dramatically and we are sure that it will be highly interesting for everybody interested in Alzheimer’s disease and other complex brain disorders. The information gained from this publication is extremely valuable in understanding complex neurodegenerative disorders. It can be no question that the idea that epigenetics plays a role in ageing, in particular Alzheimer disease, is extremely important and fascinating. Highly recommended !

Best,
JB
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